GJB3 polyclonal antibody
产品名称： GJB3 polyclonal antibody
英文名称： GJB3 polyclonal antibody
产品编号： PAB3602
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GJB3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GJB3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Molecular interaction of connexin 30.3 and connexin 31 suggests a dominant-negative mechanism associated with erythrokeratodermia variabilis.
Plantard L, Huber M, Macari F, Meda P, Hohl D.Hum Mol Genet. 2003 Dec 15;12(24):3287-94. Epub 2003 Oct 28.
- 2.
- Divergent effects of two sequence variants of GJB3 (G12D and R32W) on the function of connexin 31 in vitro.
Rouan F, Lo CW, Fertala A, Wahl M, Jost M, Rodeck U, Uitto J, Richard G.Exp Dermatol. 2003 Apr;12(2):191-7.
- 3.
- Mutation analysis of Connexin 31 (GJB3) in sporadic non-syndromic hearing impairment.
Mhatre AN, Weld E, Lalwani AK.Clin Genet. 2003 Feb;63(2):154-9.
- Entrez GeneID:
- 2707
- Protein Accession#:
- NP_076872;O75712
- Gene Name:
- GJB3
- Gene Alias:
- CX31,DFNA2,EKV,FLJ22486,MGC102938
- Gene Description:
- gap junction protein, beta 3, 31kDa
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
- Other Designations:
- OTTHUMP00000004183,OTTHUMP00000004184,connexin 31